(5) Reactivity of model compounds of reductive coenzyme NADPH coordinating to metal complex

Reductive coenzyme NADPH produce in photosynthesis is used as a reduction agent for carbon fixation, and therefore, the reduction can be applicable by increasing the reduction ability of coenzyme NADPH and the model compounds. We found that Lewis bases, Ru(II) and Re(I) complexes, enabled NADPH model compounds to be more reductive significantly by the coordination, and we are investigating the mechanim and developing new asymmetric reduction.